Naloxone in Heroin Withdrawal

Ibogaine in the treatment of heroin withdrawal.

Exogenous sodium hydrosulfide can attenuate naloxone-precipitated withdrawal syndromes and affect cAMP signaling pathway in heroin-dependent rat's nucleus accumbens.

BACKGROUND H2S is a novel type of endogenous neural regulatory factor and gaseous mediator. Exogenous H2S can increase heroin-induced learning and memory damage in rat and alleviates heroin-induced rat hippocampus damage through antioxidant and anti-apoptosis effects. OBJECTIVE Aim of this study was to identify whether hydrogen sulfide (H2S) protects heroin withdrawal rat is related with aden...

Naloxone treatment for opiate withdrawal syndrome.

a clear-cut case ofa depressed menopausal woman in family crisis. Organic illness had been excluded. The many contaminating factors from Mrs A. and her family and also within our own system impeded our diagnostic process considerably. We too initially failed to recognise the symptoms of slowly devel oping hydrocephalus, despite allearly pointers. Only once we had assimilated all the information...

Naloxone for administration by peers in cases of heroin overdose.

TO THE EDITOR: We wish to call for the removal of scheduling and legislative barriers in Australia that prevent easy access to naloxone for administration by peers to people suffering from a heroin overdose. Use of illicit opioids, typically heroin, remains the major cause of illicit drug-related mortality in this country, with at least one accidental opioid overdose currently occurring each da...

Prescribing naloxone to actively injecting heroin users: a program to reduce heroin overdose deaths.

Heroin overdose deaths have increased alarmingly in Chicago over the past decade. Naloxone, an opioid antagonist with no abuse potential, has been used to reverse opiate overdose in emergency medical settings for decades. We describe here a program to educate opiate users in the prevention of opiate overdose and its reversal with intramuscular naloxone. Participant education and naloxone prescr...